Fat Burner Powder Bulking Steroids Anastrozole (Arimidex) For Women
Arimidex (Anastrozoles) is the aromatase inhibitor of choice. Arimidex's mechanism of
action - blocking conversion of aromatizable steroids to estrogen -
is in contrast to the mechanism of action of anti-estrogens such as
clomiphene (Clomid) (Nolvadex), which block estrogen receptors in
some tissues, and activate estrogen receptors in others.
CAS No: 120511-73-1
Appearance: White crystalline powder.
Usage: An aromatase inhibitor. Used as an antineoplastic raw materials.
Potent selective triazole aromatase inhibitors, can inhibit the
cytochrome P-450 aromatase enzyme which depends blocking the
biosynthesis of estrogen, and estrogen to stimulate breast cancer
cell growth factors. Treatment of breast cancer, especially for
those with hormone relapse after adjuvant therapy after menopause
for women with advanced breast cancer.
The drug is appropriately used when using substantial amounts of
aromatizing steroids, or when one is prone to gynecomastia and
using moderate amounts of such steroids. Arimidex does not have the
side effects of aminoglutethimide (Cytadren) and can achieve a high
degree of estrogen blockade, much moreso than Cytadren. It is
possible to reduce estrogen too much with Arimidex, and for this
reason blood tests, or less preferably salivary tests, should be
taken after the first week of use to determine if the dosing is
Arimidex is a newer drug developed for the treatment of advanced
breast cancer in women. It is manufactured by Zenica
Pharmaceuticals and was approved for use in the United States at
the end of December 1995. Nastrozoles is an aromatase-inhibiting
drug approved for treatment of breast cancer after surgery, as well
as for metastasis in both pre and postmenopausal women. The
severity of breast cancer is increased by estrogen, as sexhormones
cause hyperplasia, and differentiation at estrogen receptor sites.
Anastrozoles works by inhibiting the synthesis of estrogen.
The main advantage in using arimidex over a SERM, like tamoxifen
(nolvadex), is that arimidex blocks the aromatase enzyme; thereby,
it prevents the production of estrogen in the first place. As a
comparison, Tamoxifen will hinder the estrogen receptors from
receiving the estrogen, rather than stopping production at the
source. Therefore, you'll still have estrogen floating around in
your body when you use a SERM.
|Description||White crystalline powder||Complies|
|Conform with standard IR|
Conform with standard HPLC
|Solubility||Freely soluble in methanol,acetone,ethanol and tetrahydrofuran.And
very soluble in acetonitrile||Complies|
|Total Unspecified Impurity||max. 0.2%||0.08%|
|Individual unspecified impurlty||max. 0.1%||0.05%|
|Related compound B||max. 0.2%||0.07%|
|Related compound C||max. 0.2%||0.04%|
|Related compound D||max. 0.1%||0.05%|
|Related compound E||max. 0.1%||0.06%|
|Limit of cyclohexane||max. 0.08%||ND|
|Limit of ethylacetate||max. 0.1%||0.07%|
|Residue on ignition||max. 0.1%||0.07%|
|Storage||Cool and dry|
|Conclusion||It complies to USP32 .|